US President Joe Biden said Israel appears to have only hit military targets in its retaliatory attack against Iran. Biden expressed hope that this would be the end of the conflict as the US seeks to balance its support for Israel's right to defend itself with the goal of de-escalation. Vice President Kamala Harris also emphasized the need for de-escalation while supporting Israel's right to defend itself. The US has been using its influence to calibrate a response that avoids all-out war between Israel and Iran. Israel downplayed US involvement in the strikes, while Iran blamed the US for its complicity.