Researchers at Tel Aviv University have discovered a cancer mechanism that prevents the immune system from attacking tumors, which could lead to more effective immunotherapies. The breakthrough emerged while studying the effects of ultraviolet radiation on the immune system. The researchers found that UV exposure caused an increase in the expression of a protein associated with immune response, which was also overexpressed in cancerous tumors. Treatment with antibodies relating to the protein led to substantial tumor shrinkage in animal models, even in cases where cancers had been resistant to other forms of immunotherapy. The team is now working to translate their findings into a potential treatment for human cancer patients.
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Original article source: https://www.jpost.com/health-and-wellness/article-828086
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