Israel should proceed carefully before embarking on the annexation of Judea and Samaria, as there are many complications and potential repercussions. The estimated two million Palestinians living in these areas would pose a threat to the Jewish population within Israel, and granting them citizenship could lead to a shift in power. Additionally, there is already a strong anti-Israel sentiment in the world, and annexation could further exacerbate this. However, if the US is willing to support Israel regardless of the political consequences, it may be worth considering annexation. Ultimately, Israel must carefully weigh the potential benefits and risks before making a decision.