Iran and the United States are preparing for a second round of negotiations over Tehran's nuclear program in Rome. The talks will be led by U.S. Mideast envoy Steve Witkoff and Iranian Foreign Minister Abbas Araghchi. The negotiations are seen as a historic moment, given the longstanding enmity between the two countries. The outcome of the talks could determine whether there will be a military strike on Iran's nuclear sites or if Iran will pursue an atomic weapon. Tensions in the Middle East have also been heightened by the Israel-Hamas war and U.S. airstrikes on Iranian-backed rebels in Yemen.